Exodus 8:20 Then the LORD said to Moses, “Rise up early in the morning and present yourself to Pharaoh, as he goes out to the water, and say to him, ‘Thus says the LORD, “Let my people go, that they may serve me. Or else, if you will not let my people go, behold, I will send swarms of flies on you and your servants and your people, and into your houses. And the houses of the Egyptians shall be filled with swarms of flies, and also the ground on which they stand. But on that day I will set apart the land of Goshen, where my people dwell, so that no swarms of flies shall be there, that you may know that I am the LORD in the midst of the earth. Thus I will put a division between my people and your people. Tomorrow this sign shall happen.”’” And the LORD did so. There came great swarms of flies into the house of Pharaoh and into his servants’ houses. Throughout all the land of Egypt the land was ruined by the swarms of flies. Then Pharaoh called Moses and Aaron and said, “Go, sacrifice to your God within the land.” But Moses said, “It would not be right to do so, for the offerings we shall sacrifice to the LORD our God are an abomination to the Egyptians. If we sacrifice offerings abominable to the Egyptians before their eyes, will they not stone us? We must go three days’ journey into the wilderness and sacrifice to the LORD our God as he tells us.” So Pharaoh said, “I will let you go to sacrifice to the LORD your God in the wilderness; only you must not go very far away. Plead for me.” Then Moses said, “Behold, I am going out from you and I will plead with the LORD that the swarms of flies may depart from Pharaoh, from his servants, and from his people, tomorrow. Only let not Pharaoh cheat again by not letting the people go to sacrifice to the LORD.” So Moses went out from Pharaoh and prayed to the LORD. And the LORD did as Moses asked, and removed the swarms of flies from Pharaoh, from his servants, and from his people; not one remained. But Pharaoh hardened his heart this time also, and did not let the people go.
There is no record of a specific reply from Pharaoh to this request, but since the plague came, he obviously did not soften his heart towards the LORD God or Israel. Perhaps the reaction was not described because there was no reaction; perhaps he ignored Moses’ message. This is the first mention of the idea that the land of Goshen (where most the Israelites lived) was spared in the plagues. Possibly, the people of Israel suffered at least somewhat under the previous plagues. To a large extent, they would be spared in this fourth plague. God wanted Pharaoh to know that there was something special about the people of Israel. Pharaoh refused to recognize this, so the plagues continued. (Guzik)
Pharaoh was early at his false devotions to the river; and shall we be for more sleep and more slumber, when any service to the Lord is to be done? The Egyptians and the Hebrews were to be marked in the plague of flies. The Lord knows them that are his, and will make it appear, perhaps in this world, certainly in the other, that he has set them apart for himself. Pharaoh unwillingly entered into a treaty with Moses and Aaron. He is content they should sacrifice to their God, provided they would do it in the land of Egypt. But it would be an abomination to God, should they offer the Egyptian sacrifices; and it would be an abomination to the Egyptians, should they offer to God the objects of the worship of the Egyptians, namely, their calves or oxen. Those who would offer acceptable sacrifice to God, must separate themselves from the wicked and profane. They must also retire from the world. Israel cannot keep the feast of the Lord, either among the brick-kilns or among the flesh-pots of Egypt. And they must sacrifice as God shall command, not otherwise. Though they were in slavery to Pharaoh, yet they must obey God’s commands. Pharaoh consents for them to go into the wilderness, provided they do not go so far but that he might fetch them back again. Thus, some sinners, in a pang of conviction, part with their sins, yet are loth they should go very far away; for when the fright is over, they will turn to them again. Moses promised the removal of this plague. But let not Pharaoh deal deceitfully any more. Be not deceived; God is not mocked: if we think to cheat God by a sham repentance and a false surrender of ourselves to him, we shall put a fatal cheat upon our own souls. Pharaoh returned to his hardness. Reigning lusts break through the strongest bonds, and make men presume and go from their word. Many seem in earnest, but there is some reserve, some beloved, secret sin. They are unwilling to look upon themselves as in danger of everlasting misery. They will refrain from other sins; they do much, give much, and even punish themselves much. They will leave it off sometimes, and, as it were, let their sin depart a little way; but will not make up their minds to part with all and follow Christ, bearing the cross. Rather than that, they venture all. They are sorrowful, but depart from Christ, determined to keep the world at present, and they hope for some future season, when salvation may be had without such costly sacrifices; but, at length, the poor sinner is driven away in his wickedness, and left without hope to lament his folly. (Henry)
The call of God to every individual is special and specific to them. This call on a person’s life can come at any moment and in any form that God alone chooses and ordains. This call will be in line with His Word and promises. It is hard to tell how many times this call to repentance and salvation will occur in a person’s life. I do know that at some point the heart becomes harder and more determined at rejecting and denying this call. How many people are in Hell right now that would give anything to have one more chance at redemption? How many are living right now with a hardened heart and a one-way ticket to Hell? How many reject the call of God without giving a pacing glance or nod toward eternity and things of God? Wide is the road that leads to eternal Hell and narrow is the gate to eternal Heaven – few there be that find it. Don’t let the things of this world or the wisdom of this world consume your soul. This world will go on chasing after meaningless ventures and crafty ideals, being led by people, like Pharaoh who give no thought to God and things of God.